The severity of blood cancer is related to the levels of inflammation

Experiments in human cells also discovered how rising levels of inflammation, marked by a competitive reaction of immune cells within the bone marrow

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altered the composition of immune B cells and T cells needed to fight the disease as if it were a weapon. invading bacteria or viruses.

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Using bone marrow samples from 20 adults and 22 children with the fatal disease, researchers at NYU Langone Health

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its Perlmutter Cancer Center were able to score each patient's degree of inflammation. These "iScores" were then correlated with survival rates,

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The new "iScore" device can be incorporated into existing tools to measure AML severity and used by physicians and patients as they select immunotherapy

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"Our scoring machine offers a fluid device for physicians and patients to gauge their likelihood of inflammation related to their leukemia

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The measurements needed to calculate an affected person's iScore, she says, are freely available in the follow-up manuscript for academic

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Lasry, a postdoctoral fellow at NYU Grossman School of Medicine and the Perlmutter Cancer Center, says that some patients in session

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